R&D
Ongoing Projects
Our current projects focus on the development of advanced microneedle patch technologies—from formulation design and prototype fabrication to comprehensive physicochemical and biological evaluation. These initiatives reflect our commitment to driving innovation in drug delivery and pharmaceutical research.
Research
Formulation Research
Our research team designs microneedle formulations using biocompatible polymers and sugar-based materials capable of incorporating active pharmaceutical ingredients. By considering chemical stability, dispersion, and storage conditions, we optimize compositions that enable precise control of drug release profiles and skin penetration efficiency. Additionally, moisture content and viscoelastic properties are quantitatively analyzed to ensure compatibility with the manufacturing process.
Microneedle Prototype Development
Building on formulation studies, we fabricate various types of microneedle array patches using micro-molding, precision casting, and imprinting techniques. By adjusting needle length, diameter, mechanical strength, and array density, we optimize insertion efficiency while balancing user safety and drug loading capacity. Parallel research is conducted to ensure scalability and reproducibility of the manufacturing process.
Physicochemical and Biological Evaluation
The developed microneedle prototypes undergo comprehensive evaluation of mechanical and physical properties (hardness, fracture force, insertion depth, dissolution rate) and biological performance (cytotoxicity, drug release efficiency, transdermal permeability). Using in vitro cell-based assays, ex vivo animal skin models, and Franz diffusion cell analysis, we verify whether the formulations and prototypes function effectively under biological conditions. Through this multi-layered validation, we are establishing a microneedle technology platform with proven safety and efficacy.